Indigenous tourism has been identified as a means to increase sustainable livelihoods in Canada’s Northernmost regions. These areas have traditionally relied on resource based economies and due to the issues surrounding resource extraction, climate change, and biodiversity loss are currently in transition. Communities in Canada’s Northern regions tend to be isolated with minimal infrastructure, issues related to food security and technological barriers. Compounding this are the historic impacts of colonialism and genocide which have fueled intergenerational trauma, mental and physical health issues and violence. Indigenous tourism has the potential to advance health, wealth and prosperity amongst Indigenous peoples by focusing on cultural and natural resource conservation and preservation while demonstrating a strong connection to the land and the community (Aboriginal Tourism Association of Canada, 2015). In tourism, Indigenous women entrepreneurs provide numerous benefits to their households, communities and the Canadian economy, showcasing their culture, heritage, and traditions (Zapalska & Brozik, 2017; Macpherson, Tretiakov, Mika, & Felzensztein, 2021). A collaboration between the Indigenous Tourism Association of Canada (ITAC) and the Ted Rogers School of Management, Future Skills Centre and the Diversity Institute at Toronto Metropolitan University, the Northern WE in Tourism project unites Indigenous women entrepreneurs from the Northwest Territories, Newfoundland and Labrador, Nunavut, the Yukon, and Northern Quebec in a study to identify common pathways to entrepreneurship and celebrate stories of social innovation and sustainable livelihoods. The study is informed by Indigenous women entrepreneurs and Indigenous and allied organizations from the North to share their stories of success and disappointment in pursuit of sustainable livelihoods in tourism. This presentation will explore the Indigenous focused methodologies used in co-creating this research study and share best practice case studies throughout Canada’s North that exemplify social innovation and contributing to sustainable livelihoods with Indigenous communities in Canada’s North.